Filtration In The Pharmaceutical Process

The pharmaceutical industry mainly includes the production of active pharmaceutical ingredients and biological agents. In the pharmaceutical process, a large quantity of water is required for drug production as well as equipment and drug container cleaning. To ensure the health of patients, pharmaceutical water must be free from microorganisms, pyrogens, bacterial endotoxins, particulate pollutants and other harmful substances. Therefore, professional filters are required to make the water quality meet pharmaceutical water standards. In addition, filters are also required for the recycling of catalysts used in the pharmaceutical process. Hanke is equipped with a professional technical team to provide you with customized pharmaceutical filtration solutions including ultrapure water filtration solutions and catalyst recovery & filtration solutions.

For details, please refer to:

Pharmaceutical Filtration Solutions

4 bottles of reagent are placed on the pharmaceutical production line.

Ultrapure Water Filtration
Catalyst Recovery & Filtration

Ultrapure Water Filtration

Background
Ultrapure water refers to the water that is treated to the highest level of purity for all contaminant types, i.e., water with few electrolytes other than hydrogen ions and hydroxide ions. In the pharmaceutical industry, it is mainly used for infusion solutions, injection water treatment, oral solution water treatment, pharmaceutical sterile water and artificial kidney dialysis water treatment, etc.
Problem
In the process of producing ultrapure water, impurities that are dissolved in or dispersed in water are removed as far as possible, including organics, bacteria, dust, oxides, etc. The general process of ultrapure water production includes pretreatment, reverse osmosis (RO), electrodeionization (EDI), and polishing. The RO system is the main part of the ultra-pure water production line. It uses a high-pressure pump to make raw water permeate through reverse osmosis membrane with a filter rating of 0.0001 μm under pressure while chemical ions, bacteria, fungi, and viruses are retained. Reverse osmosis membranes are very fragile and expensive. If the untreated raw water contains larger particles of impurities, it may cause damage to the reverse osmosis membrane equipment.
Solution
To protect expensive RO membranes, pretreatment is required before the RO equipment to remove large particles of contaminants that may exist. Typically, cartridge filters with a filter rating of 5 μm are adopted as they can effectively remove contaminants with a diameter of 5 microns and above, and protect the reverse osmosis equipment.

Cartridge filters for ultrapure water filtration

Catalyst Recovery & Filtration

Background
Catalyst is a substance that causes or accelerates chemical reactions without itself being affected. Almost 90% of chemical products undergo a catalytic process step during the production process.
Problem
Catalysts are commonly used for hydrogenation reactions in the pharmaceutical industry. Commonly used catalysts include nickel, palladium, ruthenium and other precious metals. These catalysts are very expensive and most companies separate and recycle the catalysts from final products through filters to save costs.
Solution
Candle filters are generally adopted for catalyst recovery & filtration as they can not only effectively recover catalysts, but also perform automatic cleaning. Besides, it operates in a fully closed environment and does no damage to the environment and employees.

Candle filters for catalyst recovery & filtration